HUMB1000 Lecture Notes - Lecture 6: Heart Valve, Ascending Aorta, Pulmonary Vein

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Pump: generating blood pressure moves blood through vessels, routing blood: separates pulmonary and systemic circulations. Blood moves through circulatory system from areas of higher to lower pressure. Cardiac cycle repetitive contraction (systole) and relaxation (diastole) of heart chambers moves blood through the heart and body. Blood flow is proportional to metabolic needs of tissues. Brain, kidneys, liver, exercising skeletal muscle very high. Cardiac output = heart rate (number of beats/min x stroke volume (amount of blood ejected by the ventricles with each beat). Increase bp with exercise- re-route blood flow away from skin and viscera towards brain and cardiac muscle in response to blood loss / injury. Epinephrine (adrenaline) from adrenal gland increase hr and sv, vasoconstriction in response to stress. Heart contracts involuntarily and has its own conduction system: action potential a rapid change in membrane potential. Acts as an electrical signal / impulse: generates it own action potentials.

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