HUMB2009 Lecture Notes - Lecture 3: Cancer, Epiphyseal Plate, Osteochondroma

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Osteochondromas: tumor that targets cartilage, extends laterally from epiphyseal plate. Giant cell tumour (osteoclastoma): targets young adults, extends from metaphysis and extends to subarticular cortex (joint space) Ewing sarcoma (genetic, teenagers, bone marrow, typically femurs, humerus, ribs and clavicle). Right chest wall based mass with destruction of the right 6th rib. The mass has a significant soft tissue element. Pain in the affected bone: occasional to severe and constant swelling at the site of the tumor. Tumors can cause night sweats or fevers. Symptoms: pain, swelling, bleeding, rupture of surrounding organs lateral compression could induce fracture ligament is flexible so it can resist force. However when the force is too strong, ligament could be damaged fracture interruption of the edge of the bone the acetabulum areas are reserved. Lateral compression type 2 reduction of the obturator foramina indicates rupture. 3d reconstruction is important in planning the surgery. Spread of contrast out of the vessels indicate trauma.

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