BIOL10005 Lecture Notes - Lecture 5: Hh Blood Group, Rh Blood Group System, Blood Type

• School: University of Melbourne
• Department: Biology
• Course: BIOL10005
• Professor: Dawn Gleeson

Document Summary

Blood groups & sex determination: blood groups. Good examples of: multiple alleles, complete dominance, co-dominance, epistasis. Foreign macromolecules that stimulates immune response (generate antibodies) Alleles determine the presence or absence of a glycoprotein (antigen) on the surface of the rbc (a and b antigens) e. g. ) Blood type a = type a antigens present, ab = both, o = none, etc. One gene locus at chromosome 9 (ia and ib are codominant, ia and ib are dominant to io) Not all antigen h are converted to antigen a or antigen b. Blood type o is universal donor, blood type ab is universal acceptor. Agglutination occurs when the same type of antigen mixes with the same type of antibody -> can do blood typing. Precursor molecule is converted to h structure (also called h antigen) (another gene locus (bombay locus) controls the production of h antigen)