NEUR30003 Lecture Notes - Lecture 19: Semantic Dementia, Prefrontal Cortex, Spatial Memory

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Lecture 8. 2 learning and memory systems. Distinction b/w explicit and implicit memory: subdivisions. Nature of working memory and key regions involved. Role of hippocampus and neocortex in formation and recall of long term explicit memory. Explicit: memory of facts/events, can be consciously recalled if short term, sometimes called working memory. Working memory stores newly acquired info and retrieved memories. Depends on prefrontal cortex (also lateral infraparietal cortex) Determines what gets transferred to short-term and long-term memory. Each component of working memory is distributed across a different set of brain regions. Also called declarative memory: divided into semantic and episodic memory includes normal working memory requires hippocampal formation for transfer from working to long term memory, ultimately transferred. Primarily stored in the neocortex once consolidated: often involves reliving original stimulus. Semantic and episodic semantic memory: content, meaning of words, sights, sounds, etc. lost first in diffuse cortical degeneration.

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