PHYS30005 Lecture Notes - Lecture 1: Skeletal Muscle, Cellular Respiration, Exercise Intensity

• School: University of Melbourne
• Department: Physiology
• Course: PHYS30005
• Professor: Professor

Document Summary

Effect of independence, productivity and quality of life. The atp dependent processes in contracting skeletal muscle. Energy systems responsible for atp generation during exercise. The relative atp generating power and capacity of these energy systems. The relative importance of the energy systems during high intensity exercise, rest- exercise transitions and prolonged endurance exercise. The influence of exercise intensity and duration on the relative importance of cho and fat for oxidative metabolism. Ec coupling (muscle contraction: dependent on release of ca2+ from sr, ca2+ allows contraction at myosin + actin level. Contraction requires energy: cross-bridge cycling atpase allows movement of myosin over actin (main site of atp utilization) ** key site, atp required to pump back ca2+ into sr, atp needed to keep membrane potential. 200w for 15s - atp required per second is 0. 4 mmol. There is a constant need to rapidly synthesize new atp. Increased intensity to 420w -> exercise for 6 s requires 1. 0 mmol atp.