LQB185 Lecture Notes - Lecture 9: Somatic Nervous System, Piriformis Muscle, Botulinum Toxin

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School
Course
Professor
Week 9 Lecture
Muscular System
Main function is movement
Neural disorders
- Multiple sclerosis
- Piriformis
- Tourettes
Physical disorders
- Muscle strain and tear
- Shrinking due to inactivity
Botox
- Blocks signals from nerves to muscle tissue
- Muscle can no longer contract causing wrinkles
Tourettes
- Inherited neurological disorder
- Uncontrollable twitches, movements
- Botox can treat numerous movements disorders
Delayed Onset Muscle Soreness
- Exercise caused
- Tears to the myofibrils in muscle cells
- Cause swelling, altered muscle firing patterns
- Causes an inflammatory response
Muscle tissues
- Skeletal- somatic nervous system, form attachments with bones,
pulley system like, striations- overlapping actin and myosin.
multinucleated
- Cardiac- heart tissue specific, can be specialised (pacemaker cells),
sympathetic speed up, parasympathetic slows down
- Smooth- hollow organs, similar contractile properties, non-striated
Stabilising joints, movement, postures, ventricles and atria, bladder,
blood vessels
Skeletal Muscles
- 600 muscles
- Full muscle
-muscle tissues, connective tissue, nervous tissue, epithelium (blood
vessels)
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Document Summary

Blocks signals from nerves to muscle tissue. Muscle can no longer contract causing wrinkles. Tears to the myofibrils in muscle cells. Skeletal- somatic nervous system, form attachments with bones, pulley system like, striations- overlapping actin and myosin. multinucleated. Cardiac- heart tissue specific, can be specialised (pacemaker cells), sympathetic speed up, parasympathetic slows down. Smooth- hollow organs, similar contractile properties, non-striated. Stabilising joints, movement, postures, ventricles and atria, bladder, blood vessels. Muscle tissues, connective tissue, nervous tissue, epithelium (blood vessels) All the way through, wrapping round muscle, access for blood supply and nerves. Muscle fibres make-up: sarcolemma= plasma membrane (lipid bilayer, sarcoplasm= cytoplasm, myofibrils= long strands of sarcomeres, sarcoplasmic reticulum. Like endoplasmic reticulum, but for ca2+ storage in muscle cells. Muscle cell is directly innervated by a motor neuron. Made up of overlapping thick myosin and thin actin filaments. Filaments slide over each other casing movement.

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