BIOL1020 Lecture Notes - Lecture 6: Polyadenylation, Intron, Heterochromatin
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2 and the transcription initiation complex that includes the mediator protein: cells often need to coordinate expression of tens or hundreds of genes scattered throughout he genome. Homeotic mutations: these types of developmental mutations in which one body part is replaced by another, are called homeotic mutations, can occur in plants or animals. Ferritin has a role in storing excess iron and releasing it when our blood iron levels drop. Ferritin production is controlled by fe levels by translational repression- when fe levels are low, there"s no need to store it within ferritin proteins. When the fe levels are high, there"s need for more ferritin protein. In this fashion, mirna executes post-transcriptional gene silencing. Summary: regulation of gene expression can occur at: chromatin remodelling, transcription, rna processing, mrna stability, translation, post-translational levels. Introns- non-coding sections: exon- coding sections that are expressed.