HUBS1403 Lecture Notes - Lecture 7: Semipermeable Membrane, Facilitated Diffusion, Passive Transport

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Lecture'7'–'Membrane'Transport'
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1. Define!“permeability”!and!describe!the!permeability!of!our!plasma!membranes.!
Permeability!is!the!state!of!allowing!substances!to!pass!through!it.!Our!plasma!membranes!our!semi=
permeable.!
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2. Recall!what!a!concentration!gradient!is.!How!does!this!relate!to!simple!diffusion?!
Concentration!gradients!work!to!ensure!there!is!even!concentration.!This!relates!to!simple!diffusion!as!it!
aims!to!have!an!equal!concentration!where!the!solute!will!move!from!an!area!of!high!concentration!to!an!
area!of!low!concentration.!
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3. What!is!active!transport?!Give!an!example.!
Active!transport!involves!transport!against!the!concentration!gradient!in!which!energy!is!required!to!
transport!substances,!e.g.!uptake!of!glucose!in!the!intestines!
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4. What!is!passive!transport?!Give!an!example.!
Active!transport!involves!transport!along!the!concentration!gradient!in!which!no!energy!is!required!to!
transport!substances,!e.g.!osmosis!
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5. List!the!5!main!things!that!can!affect!diffusion!rate!across!a!membrane.!
Size!of!molecule!
Distance!
Concentration!gradient!
Temperature!
Surface!area!
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6. Define!the!following:!
Osmosis!–!a!process!by!which!water!molecules!pass!through!a!semipermeable!membrane!from!a!
more!concentrated!solution!into!a!less!concentrated!solution!
Osmolarity!–!the!concentration!of!a!solution!expressed!as!the!total!number!of!solute!particles!per!litre!
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7. If!a!cell!is!hypertonic!water!will!move!out!of!the!cell!due!to!osmosis.!This!will!cause!the!cell!to!
decrease!in!size!and!possibly!shrivel.!!
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8. If!a!cell!is!hypotonic!water!will!move!into!the!cell!due!to!osmosis.!This!will!cause!the!cell!to!increase!in!
size!and!possibly!burst.!
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9. If!the!cell!is!isotonic!there!will!be!no!change!as!the!concentrations!on!either!side!are!equal.!
10. Describe!facilitated!diffusion.!
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11. The!Na=K!pumps!moves!3!Na+!ions!out!of!the!cell!and!2!K+!ions!into!the!cell.!
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12. List!the!broad!steps!of!the!process.!
3!Na!ions!from!the!cytosol!bind!to!the!inside!surface!of!the!pump!
Na!binding!triggers!ATP!to!bind!to!the!pump!and!be!split!into!ADP!and!P.!This!energy!causes!the!
protein!to!change!shape,!which!moves!Na!to!the!outside!
2!K!ions!land!to!the!outside!surface!of!the!pump!and!cause!the!P!to!be!released!
The!release!of!P!causes!the!pump!to!return!to!its!original!shape!and!move!K!ions!into!the!cell!
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