HUBS1404 Lecture Notes - Lecture 6: Cardiac Output, Pulmonary Artery, Stroke Volume

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Lecture 6: blood volume regulation consider how the body regulates and adjusts blood pressure and blood volume through coordinated reflexes which involve heart, blood vessels and sometimes the kidneys. Depends on time course - what is happening in the environment. Often involves a "whole body" response involving: heart, blood vessels (changing diameter, closing off certain capillary beds, kidneys, gi tract, behaviour (thirst) Requires response from the nervous and endocrine systems - for effective communication between the brain and organs. Receptors and effectors involved in regulation of bp. Your body measures arterial bp near the aorta (effectively measuring how stretched the aortic arch is). Over the short to intermediate term bp is adjusted primarily via altering the amount of blood ejected from the heart (cardiac output) and by changing the peripheral resistance by contracting or relaxing arterial smooth muscle. The circulation is a closed system: the output from the pump (heart) is the same as the blood flow.

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