ANP 1105 Lecture Notes - Lecture 17: Vasomotor Center, Blood Vessel, Vascular Smooth Muscle

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Anp1105 a dr. joanne savory and dr. m zeroual. Capillary blood pressure: low pressure; 35mmhg at entry and ~17mmhg by end of the bed. Capillaries are fragile; high pressures would rupture them. Most capillaries are extremely permeable; lots of exchange at lo bp. Venous blood pressure: steady, changes very little during cardiac cycle (gradient only ~15mmhg) Blood pressure (co and peripheral resistance) maintaining blood pressure requires cooperation of heart, blood vessels, and kidneys; all supervised by brain. 3 main factors influencing bp are: cardiac output (co = hr x sv), peripheral resistance (r), blood volume. F = dp/r and f = co if co = dp/r then dp = co x pr so if map = co x r then map = sv x hr x r. Anything that increases sv, hr, or r will also increase map. Sv is effected by venous return (edv); hr is maintained by medullary centers; r is effected mostly by vessel diameter.

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