MEDI112 Lecture Notes - Lecture 12: Vas Deferens, Corpus Spongiosum Penis, Secondary Sex Characteristic

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Sperm production spermatogenesis occurs in the 250m of seminiferous tubules. Involves germ cells and sertoli cells: testosterone production produced by leydig cells (interstitial) Increases dramatically during puberty and maintains a fairly constant level throughout the rest of the male life. Particularly sensitive to testosterone and neural inhibition pre-puberty: fhs = pulsatiley released in response to gnrh. Inhibin negatively feeds back to fsh: lh affects leydig cells. Testosterone (can negatively feedback to lh and gnrh if too much: sperm trail seminal volume = 2-5ml (ph 7-8). 60m/ml 50% motile: semineferous tubules sperm mature here before being moved out, epididymis sperm stored here (lower section) consumes fluid and residual bodies to concentrate sperm. Cilia and smooth muscle contraction moves the sperm along: vas deferens, seminal vesicles supplied 60% fluid, proteins, enzymes, fructose, mucus, vitamin c, aas, flavins, prostaglandins (smooth muscle contraction), fibrinogen (coagulation),

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