300845 Lecture Notes - Lecture 7: Sister Chromatids, Electric Field, Base Pair

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Metaphase i- homologous chromosomes line up at metaphase plate; random alignment of non-homologous chromosomes is the basis of the law of independent assortment. Anaphase i- the physical separation of homologous chromosomes to the opposite poles of spindle- demonstrates law of segregation; Meiosis ii consists of prophase ii, metaphase ii, anaphase. Ii and telophase ii which are identical to the stages of mitosis. Anaphase ii- centromeres divide and sister chromatids of each chromosome separate. Telophase ii- each cell contains haploid chromosome number one member of each homologous pair. Eukaryotic chromosomes are highly coiled complexes of a single dna molecule and protein. Chromosome size is measured in kb- kilobase pairs. Chromosomes-sized dna molecules can be separated by electrophoresis in which dna molecules move in response to electric field. Chromatin is a stable, ordered complex of dna and protein. Histones= major class of basic (small) proteins in chromatin fibers. Five major types of histones are found in chromatin: h1,

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