ANHB1101 Lecture Notes - Lecture 34: Zygote, Down Syndrome, Petri Dish
3 Jun 2018
School
Course
Professor
Lecture 34
Thursday, 2 June 2016
2:46 pm
Manipulating Reproduction 2: Infertility and Assisted Reproductive
Technologies (ART)
Waiting Time to Conception:
• Monthly probability of pregnancy - 20-25%
• Uneasy to assess best time to conceive
Infertility;
• Inability of a couple to conceive after 12 months unprotected intercourse
• Inability to carry a pregnancy to a live birth
• 1 in 6 couples experience fertility problems
Causes:
• Male factors (30%)
o Sperm production
o Sperm function
o Sperm to egg
• Female factors (30%)
o Ovulation
o Tubal factors
o Implantation
• Male and female factors combines (30%)
• Idiopathic (10%R)
Investigation of the Infertile Couple:
• General/history
o BMI
o General health
o Lifestyle
• Male
o Semen analysis
o Number, motility and morphology
o DNA fragmentation
• Female
o Ovarian reserve
o Ovulating
o Tubal patency
o Uterine factors
• Couple
o Post coital test
In-Vitro Fertilization (IVF):
• Injection of hormones stimulate follicular development
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