IMED3004 Lecture Notes - Lecture 7: Pyoderma Gangrenosum, Blood Culture, Diabetic Foot
1 Nov 2020
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Document Summary
Importance of ssti"s: one of the most common infections in all age groups. Highly diverse group of infections: anatomic distribution. Infecting organism (100"s possible: most mild but some are limb and life threatening. Disruption allows penetration of pathogens into deeper layers. Bacteria may penetrate into deeper layers via lymphatics. But, may be exaggerated in severe infections or those producing toxins. Tissue oedema: may lead to necrosis if compromised vascularity. Diagnosis of skin infections: many are clinical diagnoses, microbiology- microscopy and culture. Skin scrapings or nail clippings: microscopy and culture. Fungus is active in the advancing margin of the lesion. Red papules (small solid well circumscribed, raised skin swelling <1 cm) Itchy, pt usually not unwell: on arm, hands and face. Produces toxins (exfoliatin, enterotoxins: depends on maternal antibodies preventing dissemination. Local spread of toxin: bi: generalised spread = ssss. Tinea unguium: dermatophyte nail infection, also termed onychomycosis or fungal nail infection, may occur with tinea pedis.
