HSE110 Lecture Notes - Lecture 1: Exergonic Reaction, Intramuscular Injection, Glycogenin
Document Summary
Module 1 notes: energy transfer and metabolic fuels. When compared with resting usage of atp, skeletal muscle demand for energy can increase by 700 fold during high intensity exercise. The molecule atp consists of an adenine, a ribose, and three phosphate groups. The string of phosphate groups are bound together by strong anhydride bonds. The hydrolysis of these bonds is an exergonic reaction, thus releasing energy. Carbohydrate is stored in the body primarily in the form of glycogen, which consists of branched polymers of glucose, and a glycogenin protein at the core. The branching is optimal for rapid breakdown because it allows more points of access where glucose units can be removed for use. Glycogen within the muscle tissue can only be used by the muscle, not released into the bloodstream, due to the absence of glucose-6 phosphatase. Another source of energy for muscle contraction is lipids that are stored within the muscle, called as intramuscular triglycerides (imtgs).