MIIM20002 Lecture Notes - Lecture 26: Sarcoptes Scabiei, Aids, Hepatitis B Virus

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Secondary (skin), tertiary (brain, spinal cord, blood vessels) Effective prevention so we don"t need to treat. Diagnosis may not be clear without a test. Epidemiology of stis measuring the spread of infection. Reproductive rate ro is (cid:862)a (cid:373)easu(cid:396)e of the (cid:271)iologi(cid:272)al su(cid:272)(cid:272)ess of a(cid:374) o(cid:396)ga(cid:374)is(cid:373)(cid:863). Ro: (cid:862)a(cid:448)e(cid:396)age (cid:374)u(cid:373)(cid:271)e(cid:396) of se(cid:272)o(cid:374)da(cid:396)(cid:455) (cid:272)ases of i(cid:374)fe(cid:272)tio(cid:374) p(cid:396)odu(cid:272)ed (cid:271)(cid:455) o(cid:374)e p(cid:396)i(cid:373)a(cid:396)(cid:455) (cid:272)ase i(cid:374) a (cid:272)o(cid:373)pletel(cid:455) sus(cid:272)epti(cid:271)le populatio(cid:374)(cid:863)* Ro > 1 epidemic (disease spreads, cases increase) Ro < 1 disease eventually disappears (cid:862)r0 of se(cid:454)uall(cid:455) t(cid:396)a(cid:374)s(cid:373)issi(cid:271)le i(cid:374)fe(cid:272)tio(cid:374)s depe(cid:374)ds(cid:863) to a la(cid:396)ge e(cid:454)te(cid:374)t (cid:862)upo(cid:374) the a(cid:448)e(cid:396)age (cid:396)ate of a(cid:272)(cid:395)uisitio(cid:374) of (cid:374)e(cid:449) se(cid:454)ual pa(cid:396)t(cid:374)e(cid:396)s(cid:863) 2 of these develop disease and infects others. Reduced transmission: infection transmits but ppl do not go on to show disease. Number of contacts while infectious: core group interventions (in ppl at higher risk of being affected) and community wide behavioral change. Group of core transmitters are a target for change. National centre in hiv epidemiology & clinical research.

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