BMS1062 Lecture Notes - Lecture 17: Tata-Binding Protein, Shit, Chromatin
14 Aug 2018
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Objectives: know the life-cycle of mrna in eukaryotes and prokaryotes know the concept of a bacterial operon describe the process of transcription in eukaryotes. Mrna has the same function in all cells difference between eukaryotes and prokaryotes lie in their processing and synthesis. Prokaryotes transcription and translation occur concurrently in the cytoplasm ( has no membrane-bound nucleus) Eukaryotes has nuclear membrane, thus transcription and translation are spatially segregated unlike prokaryotic mrna, eukaryotic mrna undergoes extensive processing before it can undergo translation has 3 types of rna polymerase. Type i - rrna ( larger svedberg units) - transcribes larger types of rrna. Type 3 - trna and rrna, snrna ( found in spliceosomes) essentially the smaller types of rna. Eukaryotic mrna processing in eukaryotes, mrna is synthesized as pre-mrna pre-mrna is processed as it is transcribed addition of a 7-methyl- guanosine cap at 5" end protects from hydrolysis by exonucleases functions as an.
