LSB258 Lecture Notes - Lecture 4: Motor Cortex, Aspirin, Nociception

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17 Aug 2018
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From peripheral tissue to cns: neurotransmitters - glutamate (most common, efferent [motor] division (efferent = effect, relays information from cns out to periphery, usually results in movement or secretion, two subdivisions: Somatic division: where the target tissue is skeletal muscle. Smooth muscle: cardiac muscle, glands, two neurons connect cns to target tissue, cell body contained in cns. Synapse between neurons is called the autonomic ganglion: preganglionic neuron (neuron 1) from cns to autonomic ganglion, postganglionic neuron (neuron2; attaches to target tissue e. g. smooth muscle and starts at the autonomic ganglion, two divisions. Sympathetic division: preganglionic neurons - axon is short and release acetylcholine, postganglionic neurons - long and release noradrenaline, prepares body for action [fight or flight] [rest and digest: decreases hr, constricted pupils - reduce light. Increase gastric motility to prevent stimulus from keeping the brain actively "awake: most organs innervated by both divisions of the ans, receive neurons from both divisions of ans, have dynamically opposing effects:

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