IMED1004 Lecture Notes - Lecture 52: Vibrio Cholerae, Lipopolysaccharide, Exotoxin
30 Nov 2018
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Document Summary
Ingestion of food or water- 01 and 0139 strains of the vibrio cholerae are causative. Triggering told like receptor 4 (di lecture 2) Spread primarily via contaminated water, food and poor sanitation. Humans are only known natural host for c cholerae. Has encountered the disease before (hence has developed the b memory cell response to that strain) , has been immunized before, If she has encountered- memory response: vaccine, getting the disease stronger immune system- cleanliness effect. The probability of getting sick getting 01- getting symptoms wouldn"t be a lot stomach acid (barriers) (antacids- repressed the immune response of the stomach acid) Because america has a good sanitation system that separated the water from drinking and sanitation. Hence the cholera doesn"t have any avenue to enter the human body. Natural disasters- hurricanes- hot temperature lits of water, destruction of sanitation, people displaced etc etc. Different strains- that have different effects and.
