BIOL 235 Lecture Notes - Lecture 17: Skeletal Muscle, Bronchial Hyperresponsiveness, Fibrin
Document Summary
Acute inflammation early (almost immediate) reaction of local tissues and their blood vessels to injury. Acute inflammation has two major components: vascular and cellular. Extracellular matrix consists of fibrous proteins (collagen and elastin) Inflammatory mediators, acting together or in sequence, amplify the initial response and influence its evolution by regulating the subsequent vascular and cellular responses. > endothelial cell a single layer of cells that line the blood vessels and lymphatics. Produce antiplatelet and antithrombotic agents that maintain vessel patency and vasodilators and vasoconstrictors that regulate blood flow. Participate in process of repair that accompanies inflammation through the production of growth factors that stimulate angiogenesis (formation of new blood vessels) and extracellular matrix synthesis. > platelets cell fragments that circulate blood and involved in primary hemostasis activated, releases a number of potent inflammatory mediators, so increases vascular permeability and alters chemotactic, adhesive, and proteolytic properties of the endothelial cells.
