BIOL 235 Lecture Notes - Lecture 11: Insulin, Constipation, Kidney Failure

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18 Sep 2017
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Fluid balance at the capillary level relies on a balance between opposing forces. At the arterial end of the capillary, hydrostatic pressure is higher than oncotic pressure at the capillary so fluid is pushed out into the interstitial space. Aids in the ability for hydrostatic pressure to push things out. Towards the venous end of the capillary, much of the fluid has moved into the interstitial space leaving the solutes (in particular plasma proteins) behind which creates higher capillary osmotic pressure (=28 mmhg) This higher capillary osmotic pressure then pulls fluid back into the capillary. Interstitial colloidal osmotic pressure - some particles (i. e. - glucose & electrolytes) move from the vessel into the interstitial space pulling in a little fluid with it. Extra interstitial fluid is taken up by the lymphatics & returned to the central circulation. Important to note that the normal movement of fluid depends on the integrity of the capillary membrane.

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