40.152 Lecture Notes - Lecture 2: Diabetes Insipidus, Iodine Deficiency, Zinc Deficiency

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Water: body weight: embryo= 97% newborn=70-80% adult=60% elder=45- 55% (more fat less water, more muscle more water: location: intracellular=20% (cell), intravascular=15% (vessel), Interstitial=5% (tissue space: functions: transportation of nutrients, electrolytes, and oxygen to the cells. Determines movement through: hydrostatic: pressure by a still liquid, oncotic pressure: protein pressure, pressure gradient: difference of ends of the system, capillary law: plasma and tissue colloid osmotic and hydrostatic pressures. Capillary membrane regulate the flow of blood constituents between the interstitial and intravascular compartments: fluid balance: adh (pituitary gland->water) & aldosterone (promote sodium retention) Law of capillaries= starling: osmolality: sodium, urea(bun)=protein metabolized, glucose. Hypotonic: low osmolality (cell-> tissue: ecf->icf (0. 45% nacl, 0. 33% nacl) Hypertonic: high osmolality (tissue -> cell: ecf

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