CHYS 2P35 Lecture Notes - Lecture 10: Autism Spectrum, Frontal Lobe, Asperger Syndrome
Autism Spectrum Disorder
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Social interaction
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Communication
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Restricted, repetitive, stereotyped behavior and interests
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In the majority of cases there is intellectual impairment (IQ = 70>)
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Characterized by impairments in:
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Social Awareness
Gaze & Smile mismatch
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Lack of babbling-
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Lack of reciprocity
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Dysfunctional attachment patterns
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Theory of mind (lack of): understanding how you feel and being able to empathize with you
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Perspective taking
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Co-morbidity
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Neurobiological Abnormalities
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Abnormal EEGs
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Temporal lobe-limbic link
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Frontal lobes
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Cerebellum
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Large brain size in toddlers
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Issues with number of cells, branching, migration
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Reduced activity in frontal lobes, limbic system, amygdala
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Biochemical abnormalities
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Examples
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The Sally Anne Experiment
Normally developed children - 23/27 (85%)
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Children with Down Syndrome - 12/14 (86%)
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Children with Autism - 4/20 (20%)
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Results
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Don’t pick up on subtle cues
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Perspective taking
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Faux Pas Test
Far right of the spectrum
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Can't pick up on subtle cues
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Children with Asperger’s do not experience intellectual or language impairments
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Primary characteristic is social impairment
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Asperger’s Syndrome
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Steadily increasing
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Males 3:1 versus Females
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Prevalence
Week 10: Autism
CHYS 2P35 Page 1
Document Summary
In the majority of cases there is intellectual impairment (iq = 70>) Reduced activity in frontal lobes, limbic system, amygdala. Theory of mind (lack of): understanding how you feel and being able to empathize with you. Children with asperger"s do not experience intellectual or language impairments. Pharmaceutical companies that produced the vaccine were callously risking and sacrificing helpless children in pursuit of profit. Significant increase in the prevalence rates of autism. Autis(cid:373) defi(cid:374)itio(cid:374) was expa(cid:374)ded to i(cid:374)(cid:272)lude a (cid:862)spe(cid:272)tru(cid:373)(cid:863) Careful studies of 500 children in denmark and 2 million children in sweden. These studies showed that there was no higher incidence of autism among children who had been vaccinated than among children who had not been vaccinated. Monozygotic twin concordance rate = . 50 - . 90. Frontal lobe- most responsible part of the brain for social interaction and problem solving skills fmri studies.