SCIE 1P51 Lecture Notes - Lecture 13: American Nitrox Divers International, Diabetes Mellitus Type 1, Viral Vector
16 Sep 2016
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61 implanted; developed & looked like they were working. 3 had a successful insertion of the green gene. ***study the mechanism of the proper insertion of a gene. Through the scan, one can see the green gene = protein in that particular chromosome. Nertz et al (2009) study squirrel monkeys. Trained the monkey to look & perceive something specific. 1 in 50,000 individuals in the general population. Mutation in chm gene on the x chromosome. Affected males develop night blindness in their early years and gradually lose peripheral vision which results in legal blindness by age 40. Robert & team of researchers were the first to start after the clinical trials. Started a human clinical trial gene therapy clinical trial 2011. 6 patients injected with the gene sequence in the viral vector adenovirus two patients experienced improvement in their vision.
