PSYC 3403 Lecture Notes - Lecture 3: Esterase, Acetylcholine, Headache
23 Mar 2018
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Pharmacodynamics: (once the drug is in how does it work) Ligand-gated ion channels - will either be open by a drug or neurotransmitter. Intensity of signal determined by number of percentage of drug-receptor interaction: nt"s a(cid:374)d drugs i(cid:374)tera(cid:272)t (cid:449)ith (cid:271)i(cid:374)di(cid:374)g site o(cid:374) re(cid:272)eptors or to a(cid:374) (cid:374)ear(cid:271)y site. They have a spot where ligands can bind. Composed of alpha helical coils which form proteins in the form of a receptor. Nt"s and drugs are attracted to the receptor due to ionic forces/charge. Semipermeable membrane: is a membrane that limits what gets through. Agonist means that a drug is doing the same thing as a neurotransmitter at the receptor. A drug that helps a neurotransmitter to bind to a receptor more easily it is an agonist. A drug that prevents a neurotransmitter from binding at the receptor site is an antagonist. Ion channel receptors: carrier protein, g protein-coupled receptor, enzymes.
