BIOL 366 Lecture Notes - Lecture 17: Oogenesis, Cell Migration, Actin
Document Summary
Gurken (an ap determinant during early oogenesis) Once that protein is translated it will be in that region: gurken is yellow more in dorsal region. Actin in red (cell boundaries) as oocyte volume increases, oocyte nucleus pushed by growing. > establishes dv polarity grk active only in oocyte, torpedo active only in somatic follicle cells activated torpedo receptor protein activates mirror, a tf that represses pipe pipe is omade only in the ventral follicle cells. Pipe protein modifies the ventral vitelline envelope by sulfating its proteins. Allows gastrulation-defective protein to bind to the vitelline envelope make complex that will cleave the easter protein = active. Easter cleaves spatzle = ligand that binds to and activates toll receptor. Toll protein is a maternal product becomes activated only by binding spatzle, which is produced only on the ventral side of the egg. When you have torpedo-gurken signaling, pipe is synthesized [recruitment of another.
