BIOC 2300 Lecture Notes - Lecture 4: Phosphodiester Bond, The Double Helix, Genome Size

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Bioc2300 lecture 4: nucleic acids, genomics, and dna technology. 1953: discovery of the dna double helix watson and crick. 2018: first genetically engineered humans are born (unconfirmed) Specific to ns rare but terrible genetic diseases. Yarmouth is one of the highest incidence rates in the world. It illustrates the advancement seen in the past 40 eyars about the disease. Only 15 years ago, we narrowed the disease to a gene. Eventually, a signle mutation from glycine to tryptophan is seen to be the cause. With cripsr, gene editing may be an excellent way to go in the future. List the sources of human genome variability and the types of mutations that impact protein structure: discuss several technologies used for genomic manipulation and analysis. Nucleotides polymerize to form dna/rna: nucleotides are composed of nucleosides (composed of a nitrogenous base and a sugar)

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