BIOL 2030 Lecture Notes - Lecture 8: Catabolite Activator Protein, Cyclic Adenosine Monophosphate, Operon

• School: Dalhousie University
• Department: Biology
• Course: BIOL 2030
• Professor: Wright Jonathan

Document Summary

In combinaion with camp will allow for maximum acivaion of the diferent operons. Cap is needed to start transcripion because rna pol can"t open the dna. When glucose is added, synthesis of the lactose enzymes will decrease dramaically regardless if there is lactose (or any sugar) present. The glucose enzymes are under the consituive phenotype. Glucose and lactose present but cap isn"t bound = operon of. Glucose and no lactose or cap = operon of (because no cap and the repressor is bound) No glucose or lactose but cap = operon of (because the repressor is bound) Lactose and cap but no glucose = operon on. The rates of degradaion and synthesis afect the rates of camp in the cell. Rho-dependent: the gc content is lower in the stem, there is no string of uracils ater the stem, rho will catch up to rna polymerase when it pauses and using helicase acivity, unwind the rna and dna complex.