JOUR 3440 Lecture Notes - Lecture 19: Pleiotropy, Gene Flow, Transposable Element
24 Oct 2015
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Document Summary
Add 1 gene (from chinook salmon) to produce growth hormones. Add 1 promoter (from ocean pout) to disrupt salmon"s normal cycle, and produce growth hormone year round. Class ii transposons encode a transposase which allows them to enable transposons to be cut from genomic dna and be inserted at another location. A helper with transposase plus a vector transposon as a marker to produce transposition. Structure: insertion site duplication, l repeat - 5 prime, transposase, r repeat - 3 prime, insertion site duplication. Technique producing more than one effect especially : having multiple phenotypic expressions: aqua. Bounty fish: transposase, binary transformation system, gm improvements to sit. Antagonistic effect on 2 fitness components triggers population decline: mating partners prefer larger fish-- transgenic fish have more offspring; Predators prefer larger fish, transgenic fish experience high mortality. In 40 generations, the entire species was driven to extinction. safest gene flow scenarios: -gmo has equal or higher net fitness quality of causing allergic reactions.
