PHYL 3520 Lecture Notes - Lecture 23: Submucous Plexus, Vagus Nerve, Nucleus Ambiguus
3 Apr 2020
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Phyl 3520 lecture 23 march 16, 2020 submucosal gland secretion and host defense mechanisms. The submucosal secretions are mostly under neuropeptide control by our intrinsic nerves. The sns will densely innervate submucosal glands by secreting neuropeptides that will control the functions of the cells. Submucosal glands are inside the tissues but are connected to the surface of the epithelium via collecting ducts. Along the acini and tubules of the submucosal glands, there are ion channels (cftr). When the cell receive signal from the vip, the cftr protein is activated to regulate cl and bicarbonate flow to prevent dehydration. Water will follow pericellularly to hydrate the compartments. Ach will regulate the ion concentration and works in synergy to increase the secretion of mucin and other secretions. The pns is shown with solid lines to the left; the sns is shown with dashed lines to the right.
