PSYO 2470 Lecture Notes - Lecture 16: Hallucination, Catatonia, Substantia Nigra

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Induces physiological stress response when asking people to introduce themselves for a job interview or doing math problems: not a huge change in heart rate compared to placebo. Sometimes a separation between physiology and behavioural state. Anxiolytics: bzds, gaba agonists, commonly used in conjunction with ssris. Increase levels of serotonin in synaptic cleft: release of 5-ht into the synapse increase accumulation in synapse using mao inhibitors. Inhibits the breakdown of mao: also increase using ssris, usually used in conjunction with bzds, tricyclics, block reuptake of serotonin. Dsm5 diagnosis: depressive disorders, disruptive mood dysregulation, major depressive disorders, persistent depressive disorder. Single and recurrent depressive episodes: bipolar related disorders, bipolar i disorder, bipolar ii disorder. Symptoms of depression: many drugs used to treat are working on multiple channels, somatic symptoms, more to do with behaviour, decreases in dopamine leads to lack of motivation, decreases in serotonin leads to lowered mood.

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