PSYO 3970 Lecture Notes - Lecture 2: Tata-Binding Protein, Guanine, Transfer Rna
17 Sep 2018
School
Department
Course
Professor
Document Summary
Genes that are expressed in every single cell. Genes that encode proteins for cell-specific constitutive functions. Regulation of genes can take place in many levels such as: Modification of protein (that was just translated into). Genes are be regulated by transcription factors, such as: Activators: helps the transcription complex (by binding to general transcription factors) and help the assembly of rna polymerase. (works as a mediator) Repressors: blocks the assembly of the transcription complex and rna polymerase. The transcription complex (also known as the pre-initiation complex) consists of: activators, co-activators (which integrate signals of repressors and activators), tata- binding protein, basal transcription factors and rna polymerase. Transcription rate is dependent on the quantity of activators bind to the general transcription factors on the dna. Whoever, if a single repressor binds to the dna transcription is completely blocked. Wobble: wobble pairing lets the same trna recognize multiple codons for the amino-acid it carries.
