BIOL 111 Lecture Notes - Lecture 15: Arthropod, Aposematism, Voltage-Gated Potassium Channel

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BIOL 111 Full Course Notes
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BIOL 111 Full Course Notes
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Biol 111 lecture 15 neurons, electrochemical potential. Electro : difference in charge across the cell (neuron) membrane. Chemical : concentration gradients of ions (na+, k+ , cl- ) across cell membrane. Ion channels and ion transporter proteins control ion flux across membrane. Measuring membrane potentials: electrodes inserted into an axon can monitor electrical potential difference across membrane (membrane potential, resting potential = appx. 85 mv; na+ : +40 mv: at rest , only k+ shows sizable leak current. Therefore, resting membrane potential is dominated by k+ equilibrium potential: approx. -65 mv. Summary of action potential: depolarization: na+ channels open, na+ in. If threshold level of depolarization reached at ~- then depolarization becomes regenerative : potential 2. Repolarization: na+ channels close voltage gated k+ channels open. 50mv, action while: k + out, membrane briefly hyperpolarized, but then returns to resting potential with only k+ leak channels open ion flux during single spike barely changes the concentration gradients.

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