BIOL 112 Lecture 3: Proteins (Jan 13)

• School: McGill University
• Department: Biology
• Course: BIOL 112
• Professor: Lucy- Ann Joseph

Document Summary

Buffer makes overall solution resistant to ph change: made up by weak acid/base & its conjugate base/acid, at equivalent point, 50% of the acid/base is dissociated (e. g. ch3cooh ch3coo- + H+), this is the ph of the buffer. It reacts to both acids/bases added to the solution. Low of mass action: action of reactants or removal of products increases the reaction rate o: human blood ph 7. 4, carboxyl group is mostly dissociated. Functional group: hydroxyl oh, alcohols, phosphate po4, amino nh2, amines, (proteins, carbonyl coh/-co, aldehydes/ketones, carboxyl cooh, carboxylic acids. Coo-): polymerization makes peptide bonds between carboxyl group and amino goup, polypeptide chain primary structure (always have n-terminus nh3. +, & c-terminus : folding of polypeptide chain secondary structure ( -helix, -pleated sheet) Polypeptide backbone & h-bonds: coiled coils (intertwined 2 -helixes) present in hair. The helixes have a hydrophobic amino acid every 4th position long the chain: special amino acid proline (pro)