BIOL 200 Lecture Notes - Lecture 9: Transposable Element, Transposase, Prokaryote
Document Summary
The infested genome: ltr retrotransposons, lines and sines. Inverted repeats (terminal inverted repeats) are at the front and end in opposite orientations, surrounding the protein-coding region. 5" normal, 3" inverted and placed on the 3" end of the transposon. Transposons have to move in the gene where there are flanking repeating units target-site duplication- every time a transposon moves into a target site, it can be opened up and the transposon comes in. You get a duplication, one on the transposon and one located at the target. Target site repeats- allows for the transposon to integrate itself into the gene. Maintains a singe sequence of direct repeats after the transposon is merged same orientation on either side of the protein-coding region. Transposition of dna transposons: dna transposons move through a cut and paste" mechanism, process. Start of dna transposon in the donor dna, has flanking side beside it.
