BIOL 200 Lecture Notes - Lecture 2: Hydrophobe, Thiol, Phosphorylation

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2 Oct 2016
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Dna (transcription-representation of genome) rna (translation) protein. Ribosomes translate mrna that is isolated from e. coli. Base pairs are specific (g+c and a+t) Length- as long as several hundreds of nucleotides long. <100 to 1000s of nucleotides long ribosomal rna, transfer rna, messenger rna, micro rna only mrna gets translated into proteins. Pentose sugar is linked to a base (guac) Made of polymers of amino acids that vary in length. Has an amino end (n-terminus) and a carboxyl end (c-terminus) Can be long polypeptides or short (depends on complexity) Important: catalysis, structural, transport, regulatory (turns on and off protein activies depending on cell cues), signaling, motion. Shape depends on the primary sequence- the sequence of the amino acids that make up the monomer. Pentose sugar 5" end connected to phosphate entity by the phosphodiester bond. Purines adenine and guanine (linked on 9" position to the 1" pentose group) Pyrimidines cytosine, uracil and thymine (linked on 1" position to the pentose group)

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