BIOL 200 Lecture Notes - Lecture 16: Fusion Protein, Transfer Rna, Amine

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Charles darwin speculations about heredity, had no idea, did not know dna, rna. He became a scientist had (cid:373)o(cid:374)ey, did(cid:374)"t (cid:374)eed fu(cid:374)di(cid:374)g. The central dogma : critical aspect of biologic diversity. Proteins are linear polymers of amino acids, each has a unique aa sequence. This sequence determines directly or indirectly the properties of the protein. Ea(cid:272)h p(cid:396)otei(cid:374)"s a(cid:373)i(cid:374)o a(cid:272)id se(cid:395)ue(cid:374)(cid:272)e is spe(cid:272)ified (cid:894)e(cid:374)(cid:272)oded(cid:895) (cid:271)y (cid:374)u(cid:272)leotide sequences in mrna and ultimately in dna (gene for specific protein). Mrna: carries genetic info from dna in from of codons. Each type of aa has 1 or more trnas which bind it and which can carry it into a growing polypeptide chain. trna has a 3 nucleotide anticodon that can bpair with a codon in mrna. Rrna: associates with specific proteins to form ribosomes. One of the rrnas catalyzes the formation of a peptide bond between the n of the amino group of the incoming aa and c on the growing polypeptide chain.

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