BIOL 200 Lecture Notes - Lecture 10: Aminoacyl-Trna, Wobble Base Pair, Transfer Rna
27 May 2016
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Document Summary
4 based-paired stems + 3 loops (t cg, anticodon, d, clockwise from 3" acceptor arm: + small variable loop b/t t cg and anticodon loops. 3" a in acceptor stem is linked to amino acid: amino-acyl trna or charge trna . Amino acyl-trna synthetase required for trna to bind to corresponding amino acid: innate proofreading mechanism ensures appropriate a. a. "s are bound to trna. Due to wobble pairing: more than one trna carries the same amino acid, more than one codon base-pairs with a single trna, ability for base in wobble position to bind to more than one base. Degenerate; more than one codon encode identical information. Overlapping; up to three different reading frames: uncommonly, some mrnas make different proteins from having multiple reading frames. Large subunit: in prokaryotes: rrna + 1 additional small rrna, in eukaryotes: rrna + 2 additional small rrnas.
