BIOL 201 Lecture Notes - Lecture 9: Q Cycle, Fumaric Acid, Acid Dissociation Constant
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Document Summary
Electron transport chain: converts nadh reduction into proton gradient, etc complexes have many fe-s clusters that are used for electron transfer. Electrons are passed with decreasing free energy, increasing reduction potential of the electron carriers (measured in v, a relative value determined on an arbitrary 0) Higher reduction potential, more likely to obtain/keep electron: electrons are passed to ubiquinone (coq) A lipid like carrier, 1st molecule to receive electron after complex i. Can float freely in membrane and transport electrons between complexes. An anti-oxidant that is once thought to have some health benefits (not true!) Complex i: pumps 4 protons into intermembrane space, coq reduction coupled with proton transport. Electrons and proton transfer are separated physically. Electrons are received by coq and passed to complex ii: h in intermembrane space tends to flow backwards. A gated proton channel is needed to prevent proton flowing backwards: a transverse helix located above proton channels.
