BIOL 201 Lecture Notes - Lecture 10: Malate Dehydrogenase, Atp Synthase, Alpha-Ketoglutaric Acid
20 Feb 2018
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Quiz has been moved to monday; we will finish seeing the midterm i material on friday. Nad+ nadh transfer from cytoplasmic nadh (from glycolysis) to mitochondrial nadh. Very complicated process to shuttle electrons (cycle). Nadh of the cytoplasm to nad: malate enters matrix via pump making glutamate into -ketoglutarate making -ketoglutarate into glutamate. Uses the proton gradient (proton motive force) across the inner membrane to generate atp. Hexamer head in charge of atp synthesis. Shaft: 3 and 3 subunit, subunit. Function overview: and exits: protons enter first channel, enter c ring, spin c ring, proton exposed to channel 2. Mcgill university biol 201 prof. gary brouhard: rotation of c ring causes atp synthesis via rotation of the subunit. Rotation of subunit causes the deformation of the and subunits and causes. The c-ring rotates as protons pass through it. An arginine-210 residue with a net positive charge.
