BIOL 201 Lecture 15: Lecture 15 Notes
Document Summary
Antigen: any molecule (often a protein) that elicits an immune response (recognized by antibodies: 9-11 aa"s in length, so there are 2x1014 different antigens possible) Antibody aka immunoglobulins): proteins (present in the blood and other body uids) that bind to antigens (very speci c binding), marking them for destruction by phagocytic cells. Autoimmune diseases: an immune reaction against its own antigens (proteins): antibodies recognizing pathogens (viral) Humoral (serum components; ie: complement have proteins that can recognize bacteria/foreign pathogens) and chemical barriers. Non-speci c cell barriers (not speci c): phagocytes, mast cells, dendritic cells. B-lymphocytes: respond and produce antibodies, memory b-cells. T-lymphocytes: antigen-speci c response to increase b&t cell responses, killer. Innate = rst line, not speci c, no memory, very quick. Adaptive = slower initial response, antigen-speci c response to increase b&t cell responses, killer t-cells, memory t-cells. Clonal selection: a mechanism to respond to a specific antigen.