BIOL 202 Lecture Notes - Lecture 6: Colchicine, Prophase, Giemsa Stain
Document Summary
**prof makes mention that after lecture 4, the material is intellectually benign (since we need to memorise everything from lecture 5) **lod scores will not be on the midterm but will more than likely be on the final exam prof thinks that they are not that difficult but some ppl find it confusing. We have a short arm and a long arm (based on distance) which are separated by the centromere: short arm = p, long arm = q. In a perfect world, the dna on sister chromatids would be identical (but we know that this is not 100% true due to replication errors) The sister chromatids are stuck together by proteins called cohesin. The chromosome above would be in metaphase bc the kinetochores have already attached. Note that the kinetochore microtubules attach to the centromere and not to the dna directly. Ends of the dna = telomeres protect the dna from degradation (via dsdna break)
