BIOL 205 Lecture Notes - Lecture 18: Morphogen, Linear Function, Blastomere

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Growth of the body: growth spurt at puberty, on sensing of first signal of sexual maturity rush for max, significant changes to relative proportions of different body parts, tension-driven muscle growth. Linear growth of muscle is couple with growth of bone: driving force is the tension bone exerts on muscle, genetic basis of limb growth. Cell division and limits to cell proliferation: contact inhibition of cell division, cells have to be anchored to divide basal membrane, cells away from basal layer are differentiated and don"t divide. Cell commitment and determination: how do you know, take a cell and transplant it in another region. If it forms structure it should have differentiated. Cell type identity and unique surface features: in every case, cells sort themselves out according to their type, reorganize themselves like in the embryo, different cell types have different surface features. Early embryogenesis: establishment of three primary embryonic cell layers: cleavage by cell division starts soon after fertilization.

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