CHEM 181 Lecture Notes - Lecture 12: Metformin, Diabetes Mellitus Type 2, Harvey Cushing

• School: McGill University
• Department: Chemistry
• Course: CHEM 181
• Professor: Joe Schwarcz

Document Summary

Release hormones that controls metabolism = conversion of. Chemicals in food into substances used for energy or storage. Hypothyroidism - underactive: hashimoto"s disease = autoimmune disease, iodine deficiency. Hyperthyroidism - overactive: grave"s disease = autoimmune disease. *also cabbage goiter when too much cabbage eaten. Hypothyroidism - underactive thyroid gland = thyroid hormones. Body produce antibody against thyroid gland so enlarge. Treatment of hypothyroidism = thyroid hormone in pill form like synthroid: iodine deficiency. Problem in north america because not enough iodine in soil so. *iodized salt to prevent hypothyroidism [still problem in other countries] Hyperthyroidism - overactive thyroid gland = thyroid hormones. Protruding eyeballs: grave"s disease *bulging eyes = main characteristics. Body produce excess thyroid hormones so enlarged thyroid gland. Ex: bush & wife both had grave"s disease. Treatment of hyperthyroidism : methimazole drug , introduce radioactive. Iodine i-131: surgery to remove to block thyroid hormone formation to saturate thyroid gland so radioactivity can destroy some thyroid gland.