ANAT 262 Lecture Notes - Phospholipid, Lipid-Anchored Protein, Collagen

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The golgi is the main sorting unit of the cell; everything that comes into or goes out of the cell passes through the golgi at some point for modifications. The golgi uses cop-i vesicles and ccvs (clathrin coated vesicles: ccvs are used for transport to endosomes and to the pm; their formation is very similar to cop-ii vesicle formation. Clathrin is also found on the pm for endocytosis, which we won"t look at right now. The golgi can be separated into three components, cis, trans, and medial. The cis golgi is closer to the er while the trans golgi is closer to the plasma membrane (in terms of the secretory pathway) The trans-golgi network, tgn, comes after the golgi. The golgi can vary in size, anywhere from 3 to 20 stacks, depending on the amount of secretion in the cell. Clathrin coated vesicles also involve 2 layers, inner and outer.

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