ANAT 321 Lecture Notes - Lecture 10: Postcentral Gyrus, Excitatory Synapse, Sensory Cortex
Document Summary
Layers iii and v are made up of larger pyramidal cells - output. From primary sensory cortex to more complex sensory cortex. Tend to go to layer iv: for every step forward, there is a lot of back projections - loops, feedback loops - really important for sensory perception. Layer v from v2 projects back to layers ii and vi. Neocortex also contains morphologically and biochemically diverse inhibitory interneurons. They occupy different layers, they have biochemical differences, etc. There is a huge amount of inhibition going on in the cortex. Interneurons have short, localized axons: their effects are very localized, e. g. an interneuron may inhibit the same neuron that excited it, affects the neuron"s firing behaviour. It can also inhibit a nearby neuron so the signal becomes more localized. The inhibition breaks down, unable to control the excitation. The thickness of the various layers varies in different regions of cortex.