ANSC 326 Lecture Notes - Lecture 18: Coefficient Of Relationship, Genotype Frequency, Zygosity
14 Dec 2016
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Population genetics page 1 the closest degree of inbreeding possible, namely self-fertilization identical by descent, which means that they arose from replication of the same dna molecule in a previous generation. The inbreeding coefficient, typically denoted by the symbol f, is defined as the probability that the two alleles at a locus in an inbred individual are identical by descent. the inbreeding coefficient is equal to the probability of autozygosity. Autozygous genotypes must therefore be homozygous, whereas allozygous genotypes can be either homozygous or heterozygous. The excess of homozygous genotypes, and deficiency of heterozygous genotypes, are a direct consequence and characteristic of inbreeding. Aa: p2(1-f) + pf = p2 + pqf. Aa: 2pq(1 - f) = 2pq - 2pqf aa: q2(1 - f) + pf = q2 + pqf. This principle requires the assumption that a11 genotypes have the same fitness, which is to say that no natural selection takes place.
