BIEN 210 Lecture Notes - Lecture 9: Renewable Energy, Frequentist Probability, Synthetic Biology

• School: McGill University
• Department: Bioengineering
• Course: BIEN 210
• Professor: Sebastien Hogiu

Document Summary

Lecture 9 synthetic biology & optogenetics 06/02/18: richard feynman is responsible for the bottom-up approach, which lead to developments in nanotechnology. In 2000, reports of synthetic biological circuits by michael elowitz and stanislas. 2: some induce hyperpolarization (voltage across membrane becomes more negative, opsins are light-sensitive proteins found in photoreceptor cells, retinal = small, linear chain that changes conformation, optogenetics requires 3 main steps: Identify suitable light-responsive opsins: express these opsins, deliver light to activate channels & elicit response, benefit = ability to manipulate specific neurons that control particular functions. Information storage: red = total storage on graph, digital storage media > analog, extreme, immediate storage needed, currently will be physically impossible to match this need with current materials, solution = dna, advantages: Reads very quickly (1 bit = 1 nucleic acid) Pcr = one way to read dna sequences. Retains more at low temperatures: retention = how long memory lasts before info on it degrades.