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Lecture

BIOL 200 Lecture 2

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Department
Biology (Sci)
Course
BIOL 200
Professor
Thomas E Bureau
Semester
Winter

Description
BIOL 200 Lecture 2Nucleic Acids DNA Backbone is composed of phosphatepentosePhosphodiester bond linking sugar and phosphateEnd to end bias5 endfree phosphate group3 endsugar with free hydroxyl groupDNA and RNA synthesis proceeds in a 5 to 3 direction nucleic acids written from 5 to 3 usually eg 5CAG3CAGDNA is made of 2 polynucleotide strands wound to form a double helixBackbone is on the outside of the double helixBoth strands are antiparallelThe base pairs are complementary AT GC tripleStabilizes double helix via Hbonds between pairsHas 2 grooves major groove and minor groove regions where proteins get to bases righthanded helixTypes of DNA BDNA regular ADNA and ZDNAIN low humiditydehydrated conditions BDNA
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