BIOL 202 Lecture Notes - Lecture 5: Meiosis, Product Rule, Homologous Recombination

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We inherit our cytoplasm and organelles from out mothers. Genetic linkage is what happens when genes do not assort independently due to being on the. Filial (f) generations have an overrepresentation of parental gamete types: ex: thomas hunt morgan"s fruit fly experiment. Looking at two fly mutations: red (pr+) vs purple (pr) eyes, and normal (vg+) vs vestigial (vg) wings. Test cross between a pr+/pr-vg+/vg hybrid and a pr/pr-vg/vg hybrid does not yield a mendellian pattern in the case of offspring gametes: Parent gamete type pr+ - vg+ (parent 1, homozygous + ) pr vg (parent 2, homozygous no + ) 1339 pr - vg pr+ - vg pr - vg+ The overrepresentation of parental gamete types is a clear indication that the pr and vg genes are on the same chromosome. In this case, since the mutations are on the same chromosome, we say that they are cis to each other.

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